ONO Ayumi




Graduate School 【 display / non-display

  • The University of Shiga Prefecture  Master's Course  2015.03

Campus Career 【 display / non-display

  • University of Shiga Prefecture  School of Human Nursing  Department of Human Nursing  Lecturer   2019.04 - Now

  • University of Shiga Prefecture  School of Human Nursing  Department of Human Nursing  Assistant Professor   2015.04 - 2019.03

  • University of Shiga Prefecture  School of Human Nursing  Department of Human Nursing  Research Assistant   2012.04 - 2015.03


Papers 【 display / non-display

  • Measurement of Skin Thickness Using Ultrasonography to Test the Usefulness of Elastic Compression Stockings for Leg Edema in Pregnant Women

    Banba A., Koshiyama M., Watanabe Y., Makino K., Ikuta E., Yanagisawa N., Ono A., Nakagawa M., Seki K., Sakamoto S.I., Hara Y., Nakajima A.

    Healthcare (Switzerland)  Healthcare (Switzerland)  10 (9)    2022.09

    10.3390/healthcare10091754  Joint Work  


    Background: One of the most common treatments for leg edema during pregnancy is the use of compression stockings. The purpose of this study was to evaluate the objective effectiveness in pregnant women, by measuring the changes of skin thickness using ultrasonography. Methods: Pregnant women were diagnosed with leg edema using the pitting edema method at 36 weeks of gestation. Twenty-four pregnant women (48 legs) with leg edema spent time without wearing elastic stockings at 36–37 weeks of gestation. Then, they wore elastic stockings for one week at 37–38 weeks of gestation. We measured the grade of edema (from 0 to 3) and the skin thickness of the lower leg by portable ultrasonography at 36, 37, and 38 weeks of gestation (a before-and-after study). Results: In 24 pregnant women, thigh edema was not detected in any of the 48 legs before or after the use of elastic stockings. All 48 legs in 24 pregnant women had physiological lower leg edema, but not thigh edema. The average grade of pitting edema in each lower leg significantly decreased after using the stockings (36 weeks, 1.77 ± 0.85; 37 weeks, 1.79 ± 0.77; 38 weeks, 1.04 ± 0.74, p < 0.0001). In addition, the skin thickness of the lower legs was significantly decreased after the use of elastic stockings (36 weeks, 7.47 ± 2.45 mm; 37 weeks, 7.93 ± 2.83 mm; 38 weeks, 7.15 ± 2.35 mm, p < 0.0001). Conclusions: The wearing of elastic compression stockings on the lower legs is objectively effective for improving leg edema in pregnant women.

  • The preventive effect of dietary antioxidants on cervical cancer development

    Ono A., Koshiyama M., Nakagawa M., Watanabe Y., Ikuta E., Seki K., Oowaki M.

    Medicina (Lithuania)  Medicina (Lithuania)  56 (11)   1 - 12  2020.11

    10.3390/medicina56110604  Joint Work  


    Cervical cancer results from a continuous process, starting from a normal cervical epithelium after human papillomavirus (HPV) infection and progressing to cervical intraepithelial neoplasia (CIN), before finally developing into invasive squamous carcinoma (ISC). In recent decades, dietary antioxidants, such as vitamins, have received much attention in relation to cancer prevention. We reviewed the relevant literature to investigate the dietary and nutrient intake on cervical cancer. The intake of vitamins A and D and carotenoids may inhibit early cervical cancer development. The intake of folate may prevent or inhibit HPV infection rom progressing to various grades of CIN. The intake of vitamins C and E may widely inhibit the process of cervical cancer development. Polyphenols are often used in cases of cervical cancer in combination chemotherapy and radiation therapy. Regarding nutrients, different antioxidants may have differing abilities to intervene in the natural history of cervical diseases associated with HPV infection. Regarding foods, the intake of both vegetables and fruits containing multiple vitamins may widely suppress cervical cancer development. Most previous papers have described epidemiological studies. Thus, further research using in vitro and in vivo approaches will be needed to clarify the effects of the dietary and nutrient intake in detail.

  • The preventive effect of dietary antioxidants against cervical cancer versus promotive effect of tobacco smoking.

    Koshiyama M, Nakagawa M, Ono A.

     Healthcare  7 (162)   1 - 6  2019.12

    Joint Work  Joint(The vice charge)

  • Relationship between tobacco smoking and cervical cancer.

    Ono A,Nakagawa M, Ikuta E, Watanabe Y, Koshiyama M

     Women's Health open journal  5   19 - 21  2019.11

    Joint Work  Joint(The main charge)

Review Papers 【 display / non-display

  • The Preventive Effect of Dietary Antioxidants on Viral Infection (Coronavirus Disease-2019, Influenza and Human Papillomavirus) and the Development of Cervical Carcinogenesis

    Eri Ikuta, Masafumi Koshiyama, Miwa Nakagawa, Ayumi Ono,Yumiko Watanabe, Keiko Seki,Makiko Oowaki, Yuji Okuda

     WOMEN'S HEALTH  7 (2)   34 - 37  2021.12

     Joint Work  Joint(The vice charge)