Faculty Profiles - IMAI Eri

Papers - IMAI Eri

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Relationship of homocysteine and homocysteinerelated vitamins to bone mineral density in Japanese patients with type 2 diabetes.

Yamada C, Fujimoto S, Ikeda K, Nomura Y, Matsubara A, Kanno M, Shide K, Tanaka K, Imai E, Fukuwatari T, Shibata K, Inagaki N

Journal of Diabetes Investigation 2 233 - 239 2011

ストレプトゾトシン誘発糖尿病ラットのトリプトファン－ニコチンアミド代謝－摂取ビタミン量との関係－

今井絵理，佐野光枝，福渡努，柴田克己

日本栄養・食糧学会誌 64 313 - 321 2011

Association between 24 h urinary α-tocopherol catabolite, 2, 5, 7, 8-tetramethyl-2(2'-carboxyethyl)-6-hydroxychroman (α-CEHC) and α-tocopherol intake in intervention and cross-sectional studies.

Imai E, Tsuji T, Sano M, Fukuwatari T, Shibata K

Asia Pacific Journal of Clinical Nutrition 20 507 - 513 2011

Association between 24 hour urinary alpha-tocopherol catabolite, 2,5,7,8-tetramethyl-2(2 '-carboxyethyl)-6-hydroxychroman (alpha-CEHC) and alpha-tocopherol intake in intervention and cross-sectional studies Reviewed

Eri Imai, Tomiko Tsuji, Mitsue Sano, Tsutomu Fukuwatari, Katsumi Shibata

ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION 20 ( 4 ) 507 - 513 2011

Language：English Publishing type：Research paper (scientific journal) Publisher：H E C PRESS, HEALTHY EATING CLUB PTY LTD

The objective is to determine the association between the 24 hour urinary alpha-tocopherol catabolite, 2,5,7,8-tetramethyl-2(2'-carboxyethyl)-6-hydroxychroman (alpha-CEHC) and alpha-tocopherol intake in an intervention and a cross-sectional studies. In the 4-weeks intervention study, Japanese men (n = 10) consumed the test diet in week 1, and the test diet plus varying amounts of alpha-tocopherol in the three subsequent weeks: 21 mu mol/d alpha-tocopherol in week 2, 63 mu mol/d in week 3, and 125 mu mol/d in week 4. A significant association between alpha-tocopherol intake and urinary alpha-CEHC was observed in this strictly controlled experiment (r = 0.99, p<0.001). In the cross-sectional study, all foods consumed over 4 consecutive days were recorded in 76 free-living young subjects (1833 years). The association was weak, but a significant relationship was observed (r = 0.29, p<0.05) even in the cross-sectional study. In the cross-sectional study adults, mean estimated alpha-tocopherol intake calculated by urinary alpha-CEHC and the excretory ratio was 91% of their mean intake over the 4 days. The results show that urinary alpha-CEHC level reflected recent alpha-tocopherol intake in free-living young Japanese adults, and could be used as a measure of intake during the previous few days, both for group means and for individual rankings within a group.

Web of Science

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Tryptophan-nicotinamide Metabolism in Rats with Streptozotocin-induced Diabetes: Association of Dietary Vitamin Content:Association of Dietary Vitamin Content

Imai Eri, Sano Mitsue, Fukuwatari Tsutomu, Shibata Katsumi

Eiyo To Shokuryo 64 ( 5 ) 313 - 321 2011

Language：Japanese Publisher：Japan Society of Nutrition and Food Science

The B-group of vitamins, including vitamins B1, B2, and B6, are involved in the catabolic metabolism of tryptophan. We investigated the effects of dietary vitamin content (low, moderate and sufficient) on the catabolism of tryptophan in both diabetic and healthy rats. We found that tryptophan catabolism was not affected by differences in dietary vitamin content in both diabetic and healthy rats. However, the tryptophan-nicotinamide conversion ratio was one-third lower in diabetic rats than in healthy rats. In addition, nicotinamide catabolism differed between diabetic and healthy rats. N1-methylnicotinamide, a nicotinamide catabolite, accumulated in diabetic rats, but not in normal rats, possibly contributing to the increase in free nicotinamide. It seems likely that this increase in the level of nicotinamide inhibited the activities of poly (ADP-ribose) synthetase and histone deacetylase. These results suggest that administration of nicotinamide might offer some effects, and warrants further investigation.

DOI： 10.4327/jsnfs.64.313

CiNii Books

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Other Link： http://agriknowledge.affrc.go.jp/RN/2010815008

糖尿病患者におけるビタミン摂取量および尿中ビタミン排泄量についての検討

福井富穂，今井絵理，福渡努，岩川裕美，卯木智，前川聡，柏木厚典，柴田克己

日本病態栄養学雑誌 13 123 - 131 2010

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