論文 - 東田 一彦
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Interaction Between Sarcopenic Obesity and Nonlocomotive Physical Activity on the Risk of Depressive Symptoms in Community-Dwelling Older Adult Japanese Women 査読
Yu Osugi, Aiko Imai, Toshiyuki Kurihara, Keiko Kishigami, Kazuhiko Higashida, Kiyoshi Sanada
Journal of Aging and Physical Activity 17 1 - 17 2023年1月
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Inhibition of the mitochondrial respiratory chain reduces catecholamine‑stimulated lipolysis via increasing lactate production in 3T3‑L1 adipocytes 査読
Nodoka Takeuchi, Kazuhiko Higashida, Naoya Nakai
2023年
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Intermittent fasting reduces mouse body fat while maintaining muscle mass by regulating protein synthesis and autophagy 査読
Rikako Yoshii, Kazuhiko Higashida, Naoya Nakai
Nutrition 2023年
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Low-carbohydrate, high-fat diet, and running exercise influence bone parameters in old mice. 国際誌
Yuki Aikawa, Takenori Yamashita, Naoya Nakai, Kazuhiko Higashida
132 ( 5 ) 1204 - 1212 2022年5月
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BDK knockout skeletal muscle satellite cells exhibit enhanced protein translation initiation signal in response to BCAA in vitro 査読
Nakai N, Iida N, Kitai S, Shimomura Y, Kitaura Y, Higashida K
Biosci Biotechnol Biochem Zbac021 2022年2月
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c-Myc overexpression increases ribosome biogenesis and protein synthesis independent of mTORC1 activation in mouse skeletal muscle 査読
Mori T, Ato S, Knudsen JR, Henriquez-Olguin C, Li Z, Wakabayashi K, Suginohara T, Higashida K, Tamura Y, Nakazato K, Jensen TE, Ogasawara R.
Am J Physiol Endocrinol Metab 321 ( 4 ) 551 - 559 2021年10月
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Glucose enhances catecholamine-stimulated lipolysis via increased glycerol-3-phosphate synthesis in 3T3-L1 adipocytes and rat adipose tissue 査読
Takeuchi N, Higashida K, Li X, Nakai N.
Mol Biol Rep 48 ( 6 ) 6269 - 6276 2021年9月
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Basal and resistance exercise-induced increase in protein synthesis is impaired in skeletal muscle of iron-deficient rats
Kazuhiko Higashida, Sachika Inou, Nodoka Takeuchi, Satoru Ato, Riki Ogasawara, Naoya Nakai
111389 - 111389 2021年6月
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Ketogenic diet feeding improves aerobic metabolism property in extensor digitorum longus muscle of sedentary male rats 査読
Ogura Y, Kakehashi C, Yoshihara T, Kurosaka M, Kakigi R, Higashida K, Fujiwara SE, Akema T, Funabashi T.
Plos one 2020年10月
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Iron deficiency attenuates protein synthesis stimulated by branched-chain amino acids and insulin in myotubes. 国際誌
Kazuhiko Higashida, Sachika Inoue, Naoya Nakai
531 ( 2 ) 112 - 117 2020年10月
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Autophagy under glucose starvation enhances protein translation initiation in response to re-addition of glucose in C2C12 myotubes. 国際誌
10 ( 10 ) 2149 - 2156 2020年10月
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Iron deficiency attenuates catecholamine-stimulated lipolysis via downregulation of lipolysis-related proteins and glucose utilization in 3T3-L1 adipocytes 査読 国際誌
Higashida K, Takeuchi N, Inoue N, Hashimoto T, Nakai N
Molecular Medicine Reports 2020年3月
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Application of Molecular Hydrogen as a Novel Antioxidant in Sports Science 査読
Kawamura T, Higashida K, Muraoka I
Oxidative Medicine and Cellular Longevity 2020年1月
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Induction of Autophagy and Changes in Cellular Metabolism in Glucose Starved C2C12 Myotubes 査読
Naoya Nakai, Saki Kitai, Noriko Iida, Sachika Inoue, Ken Nakata, Taro Murakami, Kazuhiko Higashida
J Nutr Sci Vitaminol (Tokyo) . 66 ( 1 ) 41 - 47 2020年1月
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Ketogenic diet feeding improves aerobic metabolism property in extensor digitorum longus muscle of sedentary male rats. 国際誌
Yuji Ogura, Chiaki Kakehashi, Toshinori Yoshihara, Mitsutoshi Kurosaka, Ryo Kakigi, Kazuhiko Higashida, Sei-Etsu Fujiwara, Tatsuo Akema, Toshiya Funabashi
15 ( 10 ) e0241382 2020年
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A Lactate-based compound containing caffeine in addition to voluntary running exercise decreases subcutaneous fat mass and improves glucose metabolism in obese rats 査読
56 84 - 91 2019年3月
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Low-carbohydrate high-protein diet diminishes the insulin response to glucose load via suppression of SGLT-1 in mice. 国際誌
Kazuhiko Higashida, Shin Terada, Xi Li, Sachika Inoue, Noriko Iida, Saki Kitai, Naoya Nakai
83 ( 2 ) 365 - 371 2019年2月
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Time Course of Decrease in Skeletal Muscle Mitochondrial Biogenesis after Discontinuation of High-Fat Diet.
Li X, Higashida K, Kawamura T, Higuchi M
J Nutr Sci Vitaminol (Tokyo) 2018年6月
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Kawamura T, Fujii R, Li X, Higashida K, Muraoka I
33 ( 3 ) 169 - 175 2018年6月
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Leucine supplementation after mechanical stimulation activates protein synthesis via L-type amino acid transporter 1 in vitro 査読 国際誌
Nakai N, Kawano F, Murakami T, Nakata K, Higashida K.
J Cell Biochem 119 ( 2 ) 2094 - 2101 2018年2月
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PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise. 査読 国際誌
Koh JH, Hancock CR, Terada S, Higashida K, Holloszy JO, Han DH
Cell metabolism 25 ( 5 ) 1176 - 1185 2017年5月
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Effects of rapid or slow body weight reduction on intramuscular protein degradation pathways during equivalent weight loss on rats 査読
Nonaka Y., Urashima S., Inai M., Nishimura S., Higashida K., Terada S.
Physiological Research 66 ( 5 ) 823 - 831 2017年1月
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A Mechanism Underlying Preventive Effect of High-Intensity Training on Colon Cancer
Matsuo K, Sato K, Suemoto K, Miyamoto-Mikami E, Fuku N, Higashida K, Tsuji K, Xu Y, Liu X, Iemitsu M, Hamaoka T, Tabata I
Med Sci Sports Exerc 2017年
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Alternate-Day High-Fat Diet Induces an Increase in Mitochondrial Enzyme Activities and Protein Content in Rat Skeletal Muscle. 国際誌
Xi Li, Kazuhiko Higashida, Takuji Kawamura, Mitsuru Higuchi
8 ( 4 ) 203 - 203 2016年4月
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酪酸摂取がラット骨格筋における糖輸送体GLUT-4タンパク質の発現量に及ぼす影響
野中 雄大, 東田 一彦, 木村 典代, 寺田 新
体力科学 65 ( 1 ) 169 - 176 2016年2月
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【未来の扉をひらく運動の研究】 運動による抗糖尿病効果とエピジェネティクス
寺田 新, 野中 雄大, 東田 一彦
体育の科学 66 ( 1 ) 36 - 43 2016年1月
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Dehydroepiandrosterone activates AMP kinase and regulates GLUT4 and PGC-1α expression in C2C12 myotubes. 査読
Yokokawa T, Sato K, Iwanaka N, Honda H, Higashida K, Iemitsu M, Hayashi T, Hashimoto T
Biochemical and biophysical research communications 463 ( 1-2 ) 42 - 47 2015年7月
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Mixed lactate and caffeine compound increases satellite cell activity and anabolic signals for muscle hypertrophy. 査読 国際誌
Yoshimi Oishi, Hayato Tsukamoto, Takumi Yokokawa, Keisuke Hirotsu, Mariko Shimazu, Kenji Uchida, Hironori Tomi, Kazuhiko Higashida, Nobumasa Iwanaka, Takeshi Hashimoto
118 ( 6 ) 742 - 9 2015年3月
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PGC-1α mediates a rapid, exercise-induced downregulation of glycogenolysis in rat skeletal muscle. 国際誌
Sang Hyun Kim, Jin Ho Koh, Kazuhiko Higashida, Su Ryun Jung, John O Holloszy, Dong-Ho Han
593 ( 3 ) 635 - 43 2015年2月
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異なる脂質含量の食餌がラットの骨格筋ミトコンドリア酵素活性および持久性運動パフォーマンスに及ぼす影響
東田一彦, 園生智広, 藤本恵理, 樋口満
スポーツ科学研究 12 137 - 144 2015年
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Corticosterone accelerates atherosclerosis in the apolipoprotein E-deficient mouse. 国際誌
Mitsuharu Okutsu, Vitor A Lira, Kazuhiko Higashida, Jonathan Peake, Mitsuru Higuchi, Katsuhiko Suzuki
232 ( 2 ) 414 - 9 2014年2月
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【運動刺激の正体を探る】 運動刺激に伴う骨格筋代謝機能の適応
寺田 新, 東田 一彦
体育の科学 63 ( 8 ) 608 - 615 2013年8月
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β-Adrenergic Stimulation Does Not Activate p38 MAPKinase or Induce PGC-1α in Skeletal Muscle
Kim SH, Asaka M, Higashida K, Takahashi Y, Holloszy JO, Han DH
Am J Physiol Endocrinol Metab 304 ( 8 ) 844 - 852 2013年
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間欠的絶食による摂取エネルギー制限がラット骨格筋のPGC-1αおよびGLUT-4 蛋白発現量に及ぼす影響
東田 一彦、樋口 満、寺田 新
スポーツ科学研究 10 1 - 11 2013年
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Effects of alternate-day fasting on high-fat diet-induced insulin resistance in rat skeletal muscle
Higashida K, Fujimoto E, Higuchi M, Terada S
Life Sci 93 ( 5 ) 208 - 213 2013年
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Effects of Resveratrol and SIRT1 on PGC-1α Activity and Mitochondrial Biogenesis: A Reevaluation
Higashida K, Kim SH, Jung SR, Asaka M, Holloszy JO, Han DH
PLOS Biology 11 ( 7 ) e1001603 2013年
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Regulation of Skeletal muscle GLUT-4 expression by exercise and nutritional stimuli
Higashida K, Tabata I, Higuchi M, Terada S
J Phys Fitness Sports Med 2 ( 3 ) 355 - 360 2013年
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Ursolic acid stimulates mTORC1 signaling after resistance exercise in rat skeletal muscle
Ogasawara R, Sato K, Higashida K, Nakazato K, Fujita S
Am J Physiol Endocrinol Metab 305 ( 6 ) 760 - 765 2013年
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Modest hypoxia significantly reduces triglyceride content and lipid droplet size in 3T3-L1 adipocytes
Hashimoto T, Yokokawa T, Endo Y, Iwanaka N, Higashida K, Taguchi S
Biochem Biophys Res Commun 440 ( 1 ) 43 - 49 2013年
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The AMPK beta2 subunit is required for energy homeostasis during metabolic stress
Dasgupta B, Ju JS, Sasaki Y, Liu X, Jung SR, Higashida K, Lindquist D, Milbrandt J
Mol Cell Biol 32 ( 14 ) 2837 - 2848 2012年
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Ginsenoside Re rapidly reverses insulin resistance in muscles of high-fat diet fed rats
Han DH, Kim SH, Higashida K, Jung SR, Polonsky KS, Klein S, Holloszy JO
Metabolism 61 ( 11 ) 1615 - 1621 2011年
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Does calorie restriction induce mitochondrial biogenesis? A reevaluation
Hancock CR, Han DH, Higashida K, Kim SH, Holloszy JO
FASEB J 25 ( 2 ) 785 - 791 2011年
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Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance
Han DH, Hancock CR, Jung SR, Higashida K, Kim SH, Holloszy JO
PLoS One 6 ( 5 ) e19739 2011年
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Normal Adaptations to Exercise Despite Protection Against Oxidative Stress
Higashida K, Kim SH, Higuchi M, Holloszy JO, Han DH
Am J Physiol Endocrinol Metab 301 ( 5 ) 779 - 784 2011年
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Prolonged exercise training induces long-term enhancement of HSP70 expression in rat plantaris muscle
Ogata T, Oishi Y, Higashida K, Higuchi M, Muraoka I
Am J Physiol Regul Integr Comp Physiol 296 ( 5 ) 1557 - 1563 2009年
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Dissociation between PGC-1alpha and GLUT-4 expression in skeletal muscle of rats fed a high-fat diet
Higashida K, Higuchi M, Terada S
J Nutr Sci Vitaminol (Tokyo) 55 ( 6 ) 486 - 491 2009年
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Potential role of lipin-1 in exercise-induced mitochondrial biogenesis
Higashida K, Higuchi M, Terada S
Biochem Biophys Res Commun 374 ( 3 ) 587 - 591 2008年