Organization
Faculty of Advanced Engineering
Department
School of Engineering Department of Electronic Systems Engineering
Title
Associate Professor
External link
KOBAYASHI Naritaka
Education
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Osaka University Faculty of Engineering
Country： Japan
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Osaka University Graduate School, Division of Engineering
Country： Japan
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Osaka University Graduate School, Division of Engineering
Country： Japan
Degree
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博士（工学） ( 2010.3 大阪大学 )
Research Field
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走査型プローブ顕微鏡
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原子間力顕微鏡
Research Experience
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The University of Shiga Prefecture School of Engineering Department of Electronic Systems Engineering Associate Professor
2021.8
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埼玉大学 大学院理工学研究科 助教
2014.4 - 2021.7
Country：Japan
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金沢大学 理工研究域電子情報学系 日本学術振興会特別研究員
2012.4 - 2014.3
Country：Japan
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金沢大学 フロンティアサイエンス機構 研究員
2010.4 - 2012.3
Country：Japan
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大阪大学 大学院工学研究科 日本学術振興会特別研究員
2008.4 - 2010.3
Country：Japan
Association Memberships
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日本結晶成長学会
2018.7
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日本化学会
2016.11
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応用物理学会
2006.1
Research Areas
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Nanotechnology/Materials / Thin film/surface and interfacial physical properties
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Nanotechnology/Materials / Nanostructural physics
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Nanotechnology/Materials / Nanometer-scale chemistry
Committee Memberships
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マイクロプロセス・ナノテクノロジー国際会議 論文委員
2019
Committee type：Academic society
Available Technology
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原子間力顕微鏡の開発と表面・界面の超高分解能計測
Papers
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Simultaneous visualization of membrane fluidity and morphology defines adhesion signatures of cancer cells. Reviewed International journal
Takahisa Matsuzaki, Mai Fujii, Hayata Noro, Shodai Togo, Mami Watanabe, Masami Suganuma, Shivani Sharma, Naritaka Kobayashi, Ryuzo Kawamura, Seiichiro Nakabayashi, Hiroshi Y Yoshikawa
Proceedings of the National Academy of Sciences of the United States of America 121 ( 50 ) e2412914121 2024.12
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Simultaneous detection of force and tunneling current in electrolyte solution by using qPlus sensor Reviewed
Naritaka Kobayashi, Masayuki Hojo, Kengo Baba, Ken Sakuta
Review of Scientific Instruments 94 ( 7 ) 073707 2023.7
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Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon Reviewed
Mugen Taniguchi, Ryu Okumura, Takahisa Matsuzaki, Ayaka Nakatani, Kei Sakaki, Shota Okamoto, Airi Ishibashi, Haruka Tani, Momoka Horikiri, Naritaka Kobayashi, Hiroshi Y Yoshikawa, Daisuke Motooka, Daisuke Okuzaki, Shota Nakamura, Toshiyuki Kida, Akihiko Kameyama, Kiyoshi Takeda
Mucosal Immunology 16 ( 5 ) 624 - 641 2023.7
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Polar Zinc Oxide Surface in Electrolyte Solutions; An Atomic View of Reconstruction, Hydration and Surface states Reviewed
Yudai Samejima, Naritaka Kobayashi, Seiichiro Nakabayashi
Physical Chemistry Chemical Physics 23 18349 - 18358 2021.8
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Growth Enhancement of Organic Nonlinear Optical Crystals by Femtosecond Laser Ablation Reviewed
Hozumi Takahashi, Mayu Yamaji, Jun Ikeyama, Makoto Nakajima, Hideaki Kitahara, Syouei Tetsukawa, Naritaka Kobayashi, Mihoko Maruyama, Teruki Sugiyama, Shuji Okada, Yusuke Mori, Seiichiro Nakabayashi, Masashi Yoshimura, Hiroshi Y Yoshikawa
Journal of Physical Chemistry C 2021 8391 - 8397 2021.4
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Stiffness Distribution Analysis in Indentation Depth Direction Reveals Clear Mechanical Features of Cells and Organoids by using AFM Reviewed
Naritaka Kobayashi*, Shodai Togo, Takahisa Matsuzaki, Kaede Hashiseko, Ryuzo Kawamura, Masami Suganuma, Seiichiro Nakabayashi, Yosuke Yoneyama, Rie Ouchi, Takanori Takebe Hiroshi Y Yoshikawa
Applied Physics Express 13 097001 2020.8
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Simultaneous Atomic-Resolution Flexural and Torsional Imaging in Liquid by Frequency Modulation Atomic Force Microscopy Reviewed
Megumi Umemoto, Ryuzo Kawamura, Hiroshi Y Yoshikawa, Seiichiro Nakabayashi, Naritaka Kobayashi
Japanese Journal of Applied Physics 59 SIII01 2020.3
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Quantitative Evaluation of the Impact of Artificial Cell Adhesion via DNA Hybridization on E-cadherin-Mediated Cell Adhesion Reviewed
Shodai Togo, Ken Sato, Ryuzo Kawamura, Naritaka Kobayashi, Makoto Norii, Seiichiro Nakabayashi, Yuji Teramura, Hiroshi Y Yoshikawa
APL Bioengineering 4 016103 2020.1
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Morphology and Dynamics of Domains in Ergosterol or Cholesterol Containing Membranes Reviewed International coauthorship
Arturo Galván-Hernández, Naritaka Kobayashi, Jorge Hernández-Cobos, Armando Antillón, Seiichiro Nakabayashi, Iván Ortega-Blake
Biochimica et Biophysica Acta (BBA) – Biomembranes 1862 183101 2019.10
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A Molecular Dynamics Study Proposing the Existence of Statistical Structural Heterogeneity due to Chain Orientation in the POPC-Cholesterol Bilayer Reviewed
Fernando Favela-Rosales, Arturo Galván-Hernández, Jorge Hernández-Cobos, Naritaka Kobayashi, Mauricio D. Carbajal-Tinoco, Seiichiro Nakabayashi, Iván Ortega-Blake
Biophysical Chemistry 257 106275 2019.10
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Reversible Surface Functionalization of Motor Proteins for Sustainable Motility Reviewed
Keisuke Meguriya, Shiori Kikuchi, Naritaka Kobayashi, Hiroshi Y Yoshikawa, Seiichiro Nakabayashi, Ryuzo Kawamura
Japanese Journal of Applied Physics 58 SDDI01 2019.5
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Hydrogen Nanobubbles at Roughness Regulated Surfaces; Why Does the Normal Hydrogen Electrode Need a Platinized-Platinum Electrode? Reviewed
Kentaro Kashiwagi, Tamon Hattori, Yudai Samejima, Naritaka Kobayashi, Seiichiro Nakabayashi
Journal of Physical Chemistry C 123 7416 - 7424 2019.3
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Atomic-Scale Imaging of Surface and Hydration Structures of Stable and Metastable Acetaminophen Crystals by Frequency Modulation Atomic Force Microscopy Reviewed
Naritaka Kobayashi, Mihoko Maruyama, Yoichiro Mori, Suguru Fukukita, Hiroaki Adachi, Kazufumi Takano, Satoshi Murakami, Hiroyoshi Matsumura, Tsuyoshi Inoue, Masashi Yoshimura, Seiichiro Nakabayashi, Yusuke Mori, Hiroshi Y Yoshikawa
Journal of Physical Chemistry C 122 21983 - 21990 2018.9
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Electron Transfer Kinetics of Methylviologen Included in 4-Sulfonatocalix[n]arenes at Glassy Carbon Electrode; Adiabaticity and Activation Energy Reviewed
Yuki Takahashi, Takashi Fujihara, Naritaka Kobayashi, Seiichiro Nakabayashi*, Zsombor Miskolczy, László Biczók
Chemical Physics Letters 708 222 - 227 2018.8
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Self-Assembly of Anionic Pyrene Derivatives with Cationic Surfactants Bearing a Tetradecyl Chain Reviewed
Zsombor Miskolczy, Yuki Takahashi, Naritaka Kobayashi, Seiichiro Nakabayashi, Alexandre Loukanov, László Biczók
Colloids and Surface A: Physicochemical and Engineering Aspects 552 161 - 168 2018.5
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Cell Softening in Malignant Progression of Human Lung Cancer Cells by Activation of Receptor Tyrosine Kinase AXL Reviewed
Keisuke Iida, Ryo Sakai, Shota Yokoyama, Naritaka Kobayashi, Shodai Togo, Hiroshi Y Yoshikawa, Anchalee Rawangkan, Kozue Namiki, Masami Suganuma
Scientific Reports 7 17770 2017.12
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Monitoring and Extraction of Uranium in Polluted Acid Mine Drainage by Super-Paramagnetic Nanoparticles Coated with Carbon Nanodots Reviewed
Alexander Loukanov, Hibiki Udono, Ryo Takakura, Naritaka Kobayashi, Ryuzo Kawamura,Seiichiro Nakabayashi
Journal of Radioanalytical and Nuclear Chemistry 314 1149 - 1159 2017.9
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Adsorption of Galloyl Catechin Aggregates Significantly Modulates Membrane Mechanics in Absence of Biochemical Cues Reviewed
Takahisa Matsuzaki, Hiroaki Ito, Veronika Chevyreva, Ali Makky, Stefan Kaufmann, Kazuki Okano, Naritaka Kobayashi, Masami Suganuma, Seiichiro Nakabayashi, Hiroshi Y Yoshikawa, Motomu Tanaka
Physical Chemistry Chemical Physics 19 19937 - 19947 2017.7
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Structural Change of Nonionic Surfactant Self-Assembling at Electrochemically Controlled HOPG/Electrolyte Interface Reviewed
Naritaka Kobayashi, Hirokazu Saitoh, Ryuzo Kawamura, Hiroshi Y Yoshikawa, Seiichiro Nakabayashi
Journal of Electroanalytical Chemistry 799 444 - 450 2017.6
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Kinesin-Driven Active Substrate Giving Stochastic Mechanical Stimuli to Cells for Characterization Reviewed
Ryuzo Kawamura, Daiki Uehara, Naritaka Kobayashi, Seiichiro Nakabayashi, Hiroshi Y Yoshikawa
ACS Biomaterials Science and Engineering 2 2333 - 2338 2016.10
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Investigation on Nanoscale Processes on the BaF2(111) Surface in Various Solutions by Frequency Modulation Atomic Force Microscopy Reviewed
Naritaka Kobayashi, Ryuzo Kawamura, Hiroshi Y Yoshikawa, Seiichiro Nakabayashi
Journal of Applied Physics 119 214308 2016.6
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Photosensitizer-Conjugated Ultrasmall Carbon Nanodots as Multifuncional Fluorescent Probes for Bioimaging Reviewed
Alexandre Loukanov, Ryota Sekiya, Midori Yoshikawa, Naritaka Kobayashi, Yuji Moriyasu, Seiichiro Nakabayashi
Journal of Physical Chemistry C 120 15867 - 15874 2016.4
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A Relationship between Three-Dimensional Surface Hydration Structure and Force Distribution Measured by Atomic Force Microscopy Reviewed
Keisuke Miyazawa, Naritaka Kobayashi, Matthew Watkins, Alexander Shluger, Ken-ichi Amano, Takeshi Fukuma
Nanoscale 8 7334 - 7342 2016.3
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Quantitative Evaluation of Cancer Cell Adhesion to Self-Assembled Monolayer-Patterned Substrates by Reflection Interference Contrast Microscopy Reviewed
Takahisa Matsuzaki, Kosaku Ito, Kentaro Masuda, Eisuke Kakinuma, Rumi Sakamoto, Kentaro Iketaki, Hideaki Yamamoto, Masami Suganuma, Naritaka Kobayashi, Seiichiro Nakabayashi, Takashi Tanii, Hiroshi Y Yoshikawa
Journal of Physical Chemistry B 120 1221 - 1227 2016.2
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Visualizing Nanoscale Distribution of Corrosion Cells by Open-Loop Electric Potential Microscopy Reviewed
Kyoko Honbo, Shoichiro Ogata, Takuya Kitagawa, Takahiro Okamoto, Naritaka Kobayashi, Itto Sugimoto, Shohei Shima, Akira Fukunaga, Chikako Takatoh, Takeshi Fukuma
ACS Nano 10 2575 - 2583 2016.1
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Nanoscale Corrosion Behavior of Polycrystalline Copper Fine Wires in Dilute NaCl Solution Investigated by In-situ Atomic Force Microscopy Reviewed
Shoichiro Ogata, Naritaka Kobayashi, Takuya Kitagawa, Shohei Shima, Akira Fukunaga, Chikako Takatoh, Takeshi Fukuma
Corrosion Science 105 177 - 182 2016.1
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Mechanism of Atomic Force Microscopy Imaging of Three-Dimensional Hydration Structures at a Solid-Liquid Interface Reviewed
Takeshi Fukuma, Bernhard Reischl, Naritaka Kobayashi, Peter Spijker, Fillip Federici Canova, Keisuke Miyazawa, Adam S. Foster
Physical Review B 92 155412 2015.10
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Atomic-Scale Processes at the Fluorite-Water Interface Visualized by Frequency Modulation Atomic Force Microscopy Reviewed
Naritaka Kobayashi, Shirou Itakura, Hitoshi Asakawa,Takeshi Fukuma
Journal of Physical Chemistry C 117 24388 - 24396 2013.10
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Dual Frequency Open-Loop Electric Potential Microscopy for Local Potential Measurements in Electrolyte Solution with High Ionic Strength Reviewed
Naritaka Kobayashi, Hitoshi Asakawa, Takeshi Fukuma
Review of Scientific Instruments 83 033709 2012.3
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Atomic-Resolution Imaging in Liquid by Frequency Modulation Atomic Force Microscopy Using Small Cantilevers with Megahertz-Order Resonance Frequencies Reviewed
Takeshi Fukuma, Kyosuke Onishi, Naritaka Kobayashi, Atsushi Matsuki, Hitoshi Asakawa
Nanotechnology 23 135706 2012.3
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Quantitative Potential Measurements of Nanoparticles with Different Surface Charges in Liquid by Open-Loop Electric Potential Microscopy Reviewed
Naritaka Kobayashi, Hitoshi Asakawa, Takeshi Fukuma
Journal of Applied Physics 110 044315 2011.8
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Nanoscale Potential Measurements in Liquid by Frequency Modulation Atomic Force Microscopy Reviewed
Naritaka Kobayashi, Hitoshi Asakawa, Takeshi Fukuma
Review of Scientific Instruments 81 123705 2010.12
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High Force Sensitivity in Q-Controlled Phase-Modulation Atomic Force Microscopy Reviewed
Naritaka Kobayashi, Yan Jun Li, Yoshitaka Naitoh, Masami Kageshima, Yasuhiro Sugawara
Applied Physics Letters 97 011906 2010.7
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Multifrequency High-Speed Phase-Modulation Atomic Force Microscopy in Liquids Reviewed
Yan Jun Li, Kouhei Takahashi, Naritaka Kobayashi, Yoshitaka Naitoh, Masami Kageshima, Yasuhiro Sugawara
Ultramicroscopy 110 582 - 584 2010.2
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High-Speed Phase-Modulation Atomic Force Microscopy (PM-AFM) in Constant-Amplitude (CA) Mode Capable of Simultaneous Measurement of Topography and Energy Dissipation Reviewed
Yan Jun Li, Naritaka Kobayashi, Hikaru Nomura, Yoshitaka Naitoh, Masami Kageshima, Yasuhiro Sugawara
Japanese Journal of Applied Physics 47 6121 2008.7
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Phase Modulation Atomic Force Microscopy in Constant Excitation Mode Capable of Simultaneous Imaging of Topography and Energy Dissipation Reviewed
Yan Jun Li, Naritaka Kobayashi, Yoshitaka Naitoh, Masami Kageshima, Yasuhiro Sugawara
Applied Physics Letters 92 121903 2008.3
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Theoretical Investigation on Force Sensitivity in Q-Controlled Phase-Modulation Atomic Force Microscopy in Constant-Amplitude Mode Reviewed
Naritaka Kobayashi, Yan Jun Li, Yoshitaka Naitoh, Masami Kageshima, Yasuhiro Sugawara
Journal of Applied Physics 103 054305 2008.3
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Elimination of Nonlinear Cantilever Dynamics in Phase Modulation Atomic Force Microscopy (PM-AFM) in Constant Amplitude Mode Reviewed
Yasuhiro Sugawara, Naritaka Kobayashi, Masayo Kawakami, Yan Jun Li, Yoshitaka Naitoh, Masami Kageshima
Applied Physics Letters 90 194104 2007.5
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High-Sensitivity Force Detection by Phase-Modulation Atomic Force Microscopy Reviewed
Naritaka Kobayashi, Yan Jun Li, Yoshitaka Naitoh, Masami Kageshima, Yasuhiro Sugawara
Japanese Journal of Applied Physics 45 L793 - L796 2006.7
MISC
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Comparison of Hydration Structure Formed on Organic Crystal Surfaces Measured by Frequency Modulation Atomic Force Microscopy Reviewed
Naritaka Kobayashi
Japanese Journal of Applied Physics 2024.4
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Observation of Hydration Structures on Organic Crystal Surfaces by Atomic Force Microscopy and Their Comparison between Polymorphs and between Planes Reviewed
Naritaka Kobayashi, Manami Umemoto, Hiroshi Y Yoshikawa, Seiichiro Nakabayashi
49 ( 3 ) 49-3-03 2022.10
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Stiffening of Cancer Cell Membranes Is a Key Biophysical Mechanism of Primary and Tertiary Cancer Prevention with Green Tea Polyphenols Reviewed
Masami Suganuma, Anchalee Rawangkan, Pattama Wongsirisin, Naritaka Kobayashi, Takahisa Matsuzaki, Hiroshi Y Yoshikawa, Tatsuro Watanabe
Chemical and Pharmaceutical Bulletin 68 ( 12 ) 1123 - 1130 2020.12
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AFMによる細胞の新規弾性率解析および液中原子分解能計測
小林成貴, 吉川洋史, 中林誠一郎
ケミカルエンジニヤリング 64 ( 3 ) 166 - 172 2019.3
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Improvement of the Sensitivity of Phase-Modulation Atomic Force Microscopy using Q-control Technique
KOBAYASHI Naritaka, LI Yan Jun, NAITOH Yoshitaka, KAGESHIMA Masami, SUGAWARA Yasuhiro
Journal of The Surface Science Society of Japan 28 ( 9 ) 532 - 535 2007.9
Industrial property rights
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細胞の弾性特性を解析する方法，解析システム，細胞の弾性特性を可視化する方法およびプログラム
小林成貴，吉川洋史，菅沼雅美，中林誠一郎
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液中電位計測技術を用いた金属の耐食性評価方法及び評価装置
本棒享子，大橋健也，伊藤将宏，池田光晴，福間剛士，小林成貴，尾形奨一郎
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電位計測装置，及び原子間力顕微鏡
福間剛士，小林成貴
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液中電位計測装置，及び，原子間力顕微鏡
福間剛士，小林成貴，淺川雅
Awards
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第47回結晶成長国内会議講演奨励賞
2018.11 日本結晶成長学会
小林成貴
Research Projects
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液中での原子・分子直接操作技術の開発
2022 - 2024
住友財団・基礎科学研究助成
小林成貴
Authorship：Principal investigator Grant type：Competitive
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水和ネットワーク構造を１分子レベルで可視化する原子間力顕微鏡の開発
2019
服部報公会・工学研究奨励援助金
小林成貴
Authorship：Principal investigator Grant type：Competitive
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隣接水分子間に形成される水和ネットワーク構造を原子スケールで可視化するAFM技術の開発
2019
村田学術振興財団・研究助成
小林成貴
Authorship：Principal investigator Grant type：Competitive
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AFMとSTMのハイブリッド液中原子分解能計測技術の開発
Grant number：18K19052 2018.3 - 2023.3
日本学術振興会 科研費・挑戦的研究（萌芽）
小林成貴
Authorship：Principal investigator Grant type：Competitive
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電気化学的に制御された固液界面の水和構造の不均一性とナノ気泡の発生
Grant number：18H01806 2018.4 - 2021.3
日本学術振興会 科研費・基盤研究(B)
中林誠一郎
Authorship：Coinvestigator(s) Grant type：Competitive
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ナノスケール液中電位分布計測AFM技術の性能改善による実用性の向上
Grant number：17H02734 2017.4 - 2020.3
日本学術振興会 科研費・基盤研究(B)
小林成貴
Authorship：Principal investigator Grant type：Competitive
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原子レベルでの電気化学反応メカニズムの解明に資する液中原子分解能構造・物性同時計測技術の開発
2016
カシオ科学振興財団・研究助成
小林成貴
Authorship：Principal investigator Grant type：Competitive
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環境制御高速FM-AFMの開発と準安定結晶の相転移プロセスの分子分解能観察
2016
住友財団・基礎科学研究助成
小林成貴
Authorship：Principal investigator Grant type：Competitive
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がん細胞の硬化に着目した新規転移抑制物質の探索と分子構造の解明
2016
武田科学振興財団・特定研究助成
菅沼雅美
Authorship：Coinvestigator(s) Grant type：Competitive
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原子分解能を有する液中FM-AFM/STM同時観察技術の開発と光触媒反応における表面構造と電子状態の相関の解明
2016
日揮実吉奨学会・研究助成制度
Authorship：Principal investigator Grant type：Competitive
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高速液中周波数変調AFMによる原子スケールでの結晶成長メカニズムの解明
Grant number：26870221 2014.4 - 2016.3
日本学術振興会 科研費・若手研究(B)
小林成貴
Authorship：Principal investigator Grant type：Competitive
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固液界面現象の解明に資する原子間力顕微鏡による液中ナノレベル電位分布計測法の開発
Grant number：12J10544 2012.4 - 2014.3
日本学術振興会 科研費・特別研究員奨励費（PD）
小林成貴
Authorship：Principal investigator Grant type：Competitive
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３次元原子間力顕微鏡による原子スケールでの局所水和構造状態の解析方法の確立
Grant number：23760028 2011.4 - 2013.3
日本学術振興会 科研費・若手研究(B)
小林成貴
Authorship：Principal investigator Grant type：Competitive
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原子間力顕微鏡を用いた溶液中生体分子の物性マッピング手法の開発
Grant number：08J00246 2008.4 - 2010.3
日本学術振興会 特別研究員奨励費（DC2）
小林 成貴
Authorship：Principal investigator Grant type：Competitive
Presentations
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Comparison of hydration structures on organic crystal surfaces measured by FM-AFM"Atomic-scale Surface and Interfacial Structures in Liquids by Frequency Modulation Atomic Force Microscopy Invited International conference
○Naritaka Kobayashi
31st International Colloquium on Scanning Probe Microscopy 2023.12
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垂直力と水平力を同時検出可能な液中FM-AFMによる水和構造計測
○阿部拓実，川村隆三，小林成貴
第70回応用物理学会春季学術講演会 2023.3
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原子間力顕微鏡による水和物結晶表面の配位水の観察
○内藤詢平，田中彩音，作田健，小林成貴
第51回結晶成長国内会議 2022.10
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Atomic-scale Surface and Interfacial Structures in Liquids by Frequency Modulation Atomic Force Microscopy Invited International conference
○Naritaka Kobayashi
The 17th IEEE International Conference on Nano/Micro Engineered & Molecular Systems 2022.4
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液中原子間力顕微鏡による結晶表面の水和構造計測 Invited
○小林成貴
第50回結晶成長国内会議 2021.10
Teaching Experience
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ナノ計測工学
2022.4 Institution：滋賀県立大学
Level：Postgraduate
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電気電子計測Ⅰ
2022.4 Institution：滋賀県立大学
Level：Undergraduate (specialized)
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電磁気学Ⅱ
2021.9 Institution：滋賀県立大学
Level：Undergraduate (specialized)
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人間探求学（電子システム）
2022.4 Institution：滋賀県立大学
Level：Undergraduate (liberal arts)
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電子システム工学実験Ⅰ
2022.4 Institution：滋賀県立大学
Level：Undergraduate (specialized)
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電子システム工学実験Ⅳ
2022.4 Institution：滋賀県立大学
Level：Undergraduate (specialized)
Social Contribution
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電子システム工学科の紹介とセンシング工学分野の研究紹介
Role(s)： Lecturer
高大連携事業（大垣南高等学校） 2024.7
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原子や分子が見える顕微鏡
Role(s)： Lecturer
中大連携事業（河瀬中学校） 2022.9